Human Coronaviruses: A Review of Virus–Host Interactions
Identifieur interne : 001217 ( Main/Exploration ); précédent : 001216; suivant : 001218Human Coronaviruses: A Review of Virus–Host Interactions
Auteurs : Yvonne Xinyi Lim ; Yan Ling Ng ; James P. Tam ; Ding Xiang LiuSource :
- Diseases [ 2079-9721 ] ; 2016.
Abstract
Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have thrust HCoVs into spotlight of the research community due to their high pathogenicity in humans. The study of HCoV-host interactions has contributed extensively to our understanding of HCoV pathogenesis. In this review, we discuss some of the recent findings of host cell factors that might be exploited by HCoVs to facilitate their own replication cycle. We also discuss various cellular processes, such as apoptosis, innate immunity, ER stress response, mitogen-activated protein kinase (MAPK) pathway and nuclear factor kappa B (NF-κB) pathway that may be modulated by HCoVs.
Url:
DOI: 10.3390/diseases4030026
PubMed: 28933406
PubMed Central: 5456285
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Human Coronaviruses: A Review of Virus–Host Interactions</title><author><name sortKey="Lim, Yvonne Xinyi" sort="Lim, Yvonne Xinyi" uniqKey="Lim Y" first="Yvonne Xinyi" last="Lim">Yvonne Xinyi Lim</name></author><author><name sortKey="Ng, Yan Ling" sort="Ng, Yan Ling" uniqKey="Ng Y" first="Yan Ling" last="Ng">Yan Ling Ng</name></author><author><name sortKey="Tam, James P" sort="Tam, James P" uniqKey="Tam J" first="James P." last="Tam">James P. Tam</name></author><author><name sortKey="Liu, Ding Xiang" sort="Liu, Ding Xiang" uniqKey="Liu D" first="Ding Xiang" last="Liu">Ding Xiang Liu</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28933406</idno><idno type="pmc">5456285</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456285</idno><idno type="RBID">PMC:5456285</idno><idno type="doi">10.3390/diseases4030026</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">001311</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001311</idno><idno type="wicri:Area/Pmc/Curation">001311</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001311</idno><idno type="wicri:Area/Pmc/Checkpoint">000B42</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B42</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:28933406</idno><idno type="wicri:Area/PubMed/Corpus">001029</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001029</idno><idno type="wicri:Area/PubMed/Curation">001029</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001029</idno><idno type="wicri:Area/PubMed/Checkpoint">001070</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001070</idno><idno type="wicri:Area/Ncbi/Merge">001B89</idno><idno type="wicri:Area/Ncbi/Curation">001B89</idno><idno type="wicri:Area/Ncbi/Checkpoint">001B89</idno><idno type="wicri:Area/Main/Merge">001221</idno><idno type="wicri:Area/Main/Curation">001217</idno><idno type="wicri:Area/Main/Exploration">001217</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Human Coronaviruses: A Review of Virus–Host Interactions</title><author><name sortKey="Lim, Yvonne Xinyi" sort="Lim, Yvonne Xinyi" uniqKey="Lim Y" first="Yvonne Xinyi" last="Lim">Yvonne Xinyi Lim</name></author><author><name sortKey="Ng, Yan Ling" sort="Ng, Yan Ling" uniqKey="Ng Y" first="Yan Ling" last="Ng">Yan Ling Ng</name></author><author><name sortKey="Tam, James P" sort="Tam, James P" uniqKey="Tam J" first="James P." last="Tam">James P. Tam</name></author><author><name sortKey="Liu, Ding Xiang" sort="Liu, Ding Xiang" uniqKey="Liu D" first="Ding Xiang" last="Liu">Ding Xiang Liu</name></author></analytic><series><title level="j">Diseases</title><idno type="eISSN">2079-9721</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have thrust HCoVs into spotlight of the research community due to their high pathogenicity in humans. The study of HCoV-host interactions has contributed extensively to our understanding of HCoV pathogenesis. In this review, we discuss some of the recent findings of host cell factors that might be exploited by HCoVs to facilitate their own replication cycle. We also discuss various cellular processes, such as apoptosis, innate immunity, ER stress response, mitogen-activated protein kinase (MAPK) pathway and nuclear factor kappa B (NF-κB) pathway that may be modulated by HCoVs.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Pene, F" uniqKey="Pene F">F. Pene</name></author><author><name sortKey="Merlat, A" uniqKey="Merlat A">A. Merlat</name></author><author><name sortKey="Vabret, A" uniqKey="Vabret A">A. Vabret</name></author><author><name sortKey="Rozenberg, F" uniqKey="Rozenberg F">F. Rozenberg</name></author><author><name sortKey="Buzyn, A" uniqKey="Buzyn A">A. Buzyn</name></author><author><name sortKey="Dreyfus, F" uniqKey="Dreyfus F">F. Dreyfus</name></author><author><name sortKey="Cariou, A" uniqKey="Cariou A">A. 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Frieman</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Lim, Yvonne Xinyi" sort="Lim, Yvonne Xinyi" uniqKey="Lim Y" first="Yvonne Xinyi" last="Lim">Yvonne Xinyi Lim</name><name sortKey="Liu, Ding Xiang" sort="Liu, Ding Xiang" uniqKey="Liu D" first="Ding Xiang" last="Liu">Ding Xiang Liu</name><name sortKey="Ng, Yan Ling" sort="Ng, Yan Ling" uniqKey="Ng Y" first="Yan Ling" last="Ng">Yan Ling Ng</name><name sortKey="Tam, James P" sort="Tam, James P" uniqKey="Tam J" first="James P." last="Tam">James P. Tam</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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